| Hepatopulmonary syndrome in noncirrhotic portal hypertensive patients. | |
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MedLine Citation:
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PMID: 12757170 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hepatopulmonary syndrome has yet not been sufficiently assessed in noncirrhotic portal hypertension. The prevalence of hepatopulmonary syndrome was determined in 31 consecutive patients with noncirrhotic portal hypertension (19 idiopathic portal hypertension, 7 portal vein thrombosis, 5 congenital hepatic fibrosis) and 46 patients with liver cirrhosis. Contrast echocardiography was carried out in all patients. Macroaggregated albumin lung perfusion scans were performed in patients with positive contrast echocardiogram. Hepatopulmonary syndrome was detected in 5 (10.8%) cirrhotic and 3 (9.7%) noncirrhotic portal hypertensive patients (2 idiopathic portal hypertension, 1 portal vein thrombosis). All patients with hepatopulmonary syndrome had an increased shunt fraction (13-62%) and a decreased diffusion capacity of carbon monoxide (40-79%), and 7 of them were hypoxemic (PaO2, 31.6-69.8 mm Hg). These findings show that hepatopulmonary syndrome may occur in both liver cirrhosis and noncirrhotic portal hypertension and that portal hypertension is the predominant etiopathogenic factor related to hepatopulmonary syndrome. |
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Authors:
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Sabahattin Kaymakoglu; Tevfik Kahraman; Hasan Kudat; Kadir Demir; Yilmaz Cakaloglu; Isik Adalet; Dinc Dincer; Fatih Besisik; Güngör Boztas; Ahmet Bilge Sözen; Zeynel Mungan; Atilla Okten |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 48 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-05-21 Completed Date: 2003-08-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: United States |
Other Details:
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Languages: eng Pagination: 556-60 Citation Subset: AIM; IM |
Affiliation:
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Division of Gastroenterology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Blood Gas Analysis Echocardiography / methods Female Hepatopulmonary Syndrome / blood, etiology*, radionuclide imaging Humans Hypertension, Portal / blood, complications*, radionuclide imaging Liver / pathology Liver Cirrhosis / blood, complications, radionuclide imaging Lung / pathology, radionuclide imaging Male Middle Aged Spirometry Technetium Tc 99m Aggregated Albumin / diagnostic use Tomography, Emission-Computed / methods |
| Chemical | |
Reg. No./Substance:
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0/Technetium Tc 99m Aggregated Albumin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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