Document Detail


Hepatoprotective effect of Pterocarpus marsupium against carbon tetrachloride induced damage in albino rats.
MedLine Citation:
PMID:  22557255     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Medicinal plants play a key role in human health care. Pterocarpus marsupium is one of the plants used in treatment of diabetes mellitus and the present study was aimed to assess hepatoprotective effect of the plant against CCl(4) induced hepatotoxicity. Wistar albino rats were divided into four groups. Group I was normal control group; Group II, the hepatotoxic group was given CCl(4) (2ml/kg body weight intraperitoneally); Groups III received CC1(4) + Plant extract (100 mg/kg b.w orally); Group IV received only the plant extract. Liver markers were assayed in serum and liver tissue. Levels of marker enzymes such as alanine transminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) and bilirubin were increased significantly in Group II. These enzymes were significantly decreased in Group III treated with plant extracts. The present investigation suggest that the plant had a good protective effect on CCl(4) induced hepatic injury.
Authors:
D Devipriya; S Gowri; T R Nideesh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ancient science of life     Volume:  27     ISSN:  0257-7941     ISO Abbreviation:  Anc Sci Life     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2012-05-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8307589     Medline TA:  Anc Sci Life     Country:  India    
Other Details:
Languages:  eng     Pagination:  19-25     Citation Subset:  -    
Affiliation:
PG and Research, Department of Biochemistry, Dr. N.G.P Arts and Science College, Kovai Medical Centre for Research and Education Trust, Coimbatore-641 035, India.
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