Document Detail


Hepatocyte polarization is essential for the productive entry of the hepatitis B virus.
MedLine Citation:
PMID:  21953491     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: HBV enters hepatocytes via the basolateral membrane. This model, at least partially, explains the difference of PHH and HepaRG cells in infection efficacy, provides insights into natural HBV infection, and establishes a basis for optimization of the HepaRG infection system.
Authors:
Andreas Schulze; Kerry Mills; Thomas S Weiss; Stephan Urban
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-12-16
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  55     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-30     Completed Date:  2012-03-25     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  373-83     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 American Association for the Study of Liver Diseases.
Affiliation:
Department of Infectious Diseases, Molecular Virology, Otto-Meyerhof-Zentrum, University Hospital Heidelberg, Heidelberg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Cell Line, Tumor
Cell Polarity*
Hepatitis B / virology
Hepatitis B virus / physiology*
Hepatocytes / virology*
Host-Pathogen Interactions*
Humans
Intercellular Junctions
Virus Internalization*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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