| Hepatocellular carcinoma: use of color Doppler US to evaluate response to treatment with percutaneous ethanol injection. | |
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MedLine Citation:
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PMID: 7997536 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To determine the usefulness of color Doppler ultrasound (US) in the evaluation of the response of hepatocellular carcinoma (HCC) to percutaneous ethanol injection (PEI). MATERIALS AND METHODS: Forty-one patients with 48 lesions 2-5 cm in diameter underwent color Doppler US before and after PEI. Computed tomography (CT), magnetic resonance (MR) imaging, and percutaneous biopsy were also performed to help establish the outcome of therapy. RESULTS: Before treatment, color signals with an arterial Doppler spectrum were seen in 44 of 48 lesions with a frequency shift of 0.51-4.11 kHz (mean, 1.65 kHz). After PEI, 37 of these lesions showed no color signal and were found to be necrotic at CT, MR imaging, and biopsy. In six of seven lesions containing residual tumor, pulsatile flow was still identified, although the frequency shift was significantly decreased (P = .01). CONCLUSION: Color Doppler US proved useful in the assessment of the therapeutic effect of PEI on HCC. |
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Authors:
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R Lencioni; D Caramella; C Bartolozzi |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Radiology Volume: 194 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1995 Jan |
Date Detail:
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Created Date: 1995-01-17 Completed Date: 1995-01-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 113-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, University of Pisa, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Biopsy, Needle Carcinoma, Hepatocellular / blood supply, therapy*, ultrasonography* Ethanol / administration & dosage, therapeutic use* Female Humans Injections, Intralesional Liver Neoplasms / blood supply, therapy*, ultrasonography* Magnetic Resonance Imaging Male Middle Aged Tomography, X-Ray Computed Ultrasonography, Doppler, Color |
| Chemical | |
Reg. No./Substance:
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64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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