| Hepatocellular carcinoma during pregnancy: is hepatocellular carcinoma more aggressive in pregnant patients? | |
| | |
MedLine Citation:
|
PMID: 21116657 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
BACKGROUND/PURPOSE: Hepatocellular carcinoma (HCC) during pregnancy is a very rare condition and is believed to have a worse prognosis than HCC in non-pregnant women. We evaluated the prognosis and the diagnostic and therapeutic strategies for HCC in pregnant women. METHODS: We retrospectively analyzed 4 cases in our hospital and 44 cases described in the medical literature since 1957; we also compared the cases reported before 1995 and those reported during/after 1995. RESULTS: The overall 6-month and 1-, 2-, and 3-year survival rates in the patients reported in the literature were 50, 29.5, 18.2, and 13.6%, respectively (n = 44). The mean ages at diagnosis before and during/after 1995 were 31.4 ± 7.2 and 28.9 ± 4.4 years, respectively (P = 0.113). The following characteristics were significantly more common in the later group: fewer pregnancies; the absence of advanced signs or symptoms; receipt of therapy; tendency to undergo surgery; and higher 6-month and 1-, 2-, and 3-year survival rates. The median survivals of the groups before and during/after 1995 were 18 and 25.5 months, respectively (P < 0.001). CONCLUSIONS: The morbidity and mortality of HCC during pregnancy has improved over time, as diagnoses have tended to be made earlier and patients have tended to receive surgical and other treatments. |
| | |
Authors:
|
Kang Kook Choi; Young Ju Hong; Sae Byeol Choi; Young Nyun Park; Jin Sub Choi; Woo Jung Lee; Kyung Sik Kim |
Related Documents
:
|
1603497 - Determinants of parental decision to abort or continue after non-aneuploid ultrasound-d... 9272897 - The impact of mississippi's mandatory delay law on abortions and births. 1211837 - First trimester abortion by vacuum aspiration. 12452467 - Factors affecting the outcome of early medical abortion: a review of 4132 consecutive c... 10472497 - Trajectories of fetal loss in the czech republic. 2180877 - Physiological mechanisms controlling anestrus and infertility in postpartum beef cattle. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of hepato-biliary-pancreatic sciences Volume: 18 ISSN: 1868-6982 ISO Abbreviation: J Hepatobiliary Pancreat Sci Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-05-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101528587 Medline TA: J Hepatobiliary Pancreat Sci Country: Japan |
Other Details:
|
Languages: eng Pagination: 422-31 Citation Subset: IM |
Affiliation:
|
Kwandong Graduate School of Medicine, Gangneung-si, Gangwon-do, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Endoscopic ultrasonography-guided ablation therapy.
Next Document: Effect of divided supplementation of remifentanil on seizure duration and hemodynamic responses duri...