| Hepatocarcinogenesis in liver cirrhosis: imaging diagnosis. | |
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MedLine Citation:
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PMID: 9610609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hepatocellular carcinoma (HCC) frequently occurs in association with liver cirrhosis, as chronic liver disease is one of the most important factors in carcinogenesis. In addition to HCCs, recent reports of pathologic studies of resected specimens from cirrhotic liver describe associated small nodular lesions such as regenerative nodule, dysplastic nodule (adenomatous hyperplasia), and dysplastic nodule with subfocus of HCC (early HCC). In hepatocarcinogenesis of the cirrhotic liver, a regenerative nodule might be the first step in the development of HCC, going through phases of dysplastic nodule, early HCC and early advanced HCC in a multistep fashion. Fortunately, recent advances in various imaging techniques have facilitated the verification of these nodules. In this review, new nomenclature of small hepatocellular nodules, and detection and characterization of hepatic nodules in carcinogenesis with various imaging techniques are described with focus on the premalignant lesions and early stage of HCC. In addition, the efficacy of various imaging techniques for diagnosing them is discussed. Although the terms and definitions of these nodules are still variable and controversial, familiarity with the concept of these borderline lesions is important. |
Authors:
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B I Choi |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of Korean medical science Volume: 13 ISSN: 1011-8934 ISO Abbreviation: J. Korean Med. Sci. Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-08-10 Completed Date: 1998-08-10 Revised Date: 2011-03-16 |
Medline Journal Info:
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Nlm Unique ID: 8703518 Medline TA: J Korean Med Sci Country: KOREA |
Other Details:
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Languages: eng Pagination: 103-16 Citation Subset: IM |
Affiliation:
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Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Korea. choibi@radcom.snu.ac.kr |
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| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoma, Hepatocellular
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complications,
diagnosis*,
pathology Diagnostic Imaging* / methods Humans Liver Cirrhosis / complications, diagnosis*, pathology Patient Care Management Terminology as Topic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Korean Med Sci Journal ID (pmc): jkms ISSN: 1011-8934 ISSN: 1598-6357 Publisher: Korean Academy of Medical Sciences |
Article Information Download PDF  Print publication date: Month: 4 Year: 1998 Volume: 13 Issue: 2 First Page: 103 Last Page: 116 ID: 3054481 PubMed Id: 9610609 |
| Hepatocarcinogenesis in liver cirrhosis: imaging diagnosis. | |
| B. I. Choi | Email: choibi@radcom.snu.ac.kr |
| Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Korea. |
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