| Hepatitis E virus infection among pig handlers in Accra, Ghana. | |
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MedLine Citation:
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PMID: 20575309 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the correlates of hepatitis E virus infection (HEV) in a sample of persons who work with pigs. DESIGN: Cross-sectional study. SETTING: Three pig farms in the Greater Accra Region of Ghana. SUBJECTS: Persons who work with pigs seen at the selected pig farms between the months of January and May 2008. RESULTS: One hundred and five persons who work with pigs voluntarily completed a risk-factor questionnaire and provided blood samples for unlinked anonymous testing for the presence of antibodies to HEV. The median age of participants was 36.5 +/- 15.0 years (range 12-65 years). Of the 105 subjects tested, HEV seroprevelance was 38.1%. On multivariate analysis, the independent determinants of HEV infection were being employed on the farm for less than six months (odds ratio (OR) 9.1; 95% confidence interval (95% CI) 1.0-81.4 and having piped water in the household and/or on the farm (OR 3.9; 95% CI 0.4-90.8). CONCLUSION: Consistent with similar studies worldwide, the results of our studies revealed a high prevalence of HEV infection in persons who work with pigs. Further studies need to be done to isolate, characterise the virus and define the clinical and epidemiological significance of HEV infection in this population. |
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Authors:
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A A Adjei; J T Aviyase; Y Tettey; C Adu-Gyamfi; J A A Mingle; P F Ayeh-Kumi; T K Adiku; R K Gyasi |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: East African medical journal Volume: 86 ISSN: 0012-835X ISO Abbreviation: East Afr Med J Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2010-06-25 Completed Date: 2010-07-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372766 Medline TA: East Afr Med J Country: Kenya |
Other Details:
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Languages: eng Pagination: 359-63 Citation Subset: IM |
Affiliation:
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Department of Pathology, University of Ghana Medical School, College of Health Sciences, Accra, Ghana. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Agricultural Workers' Diseases Animal Husbandry Animals Cross-Sectional Studies Female Ghana / epidemiology Hepatitis E / diagnosis, epidemiology*, veterinary, virology Hepatitis E virus / immunology, isolation & purification* Humans Immunoglobulin G / blood Immunoglobulin M / blood Male Middle Aged Occupational Exposure Prevalence Swine Swine Diseases / epidemiology*, virology Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin G; 0/Immunoglobulin M |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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