| Hepatitis C virus infection enhances TNFα-induced cell death via suppression of NF-κB. | |
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MedLine Citation:
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PMID: 22430873 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONCLUSION: HCV infection enhances TNF-α-induced cell death by suppressing NF-κB activation through the action of core, NS4B, and NS5B. This mechanism may contribute to immune-mediated liver injury in HCV infection. |
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Authors:
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Junseong Park; Wonseok Kang; Seung-Wook Ryu; Woo-Il Kim; Dong-Yeop Chang; Dong Ho Lee; Do Youn Park; Youn-Hee Choi; Kyungsun Choi; Eui-Cheol Shin; Chulhee Choi |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2012-07-26 |
Journal Detail:
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Title: Hepatology (Baltimore, Md.) Volume: 56 ISSN: 1527-3350 ISO Abbreviation: Hepatology Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-08-29 Completed Date: 2012-10-30 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 8302946 Medline TA: Hepatology Country: United States |
Other Details:
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Languages: eng Pagination: 831-40 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 American Association for the Study of Liver Diseases. |
Affiliation:
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Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Death
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physiology* Cells, Cultured Hepatitis C / immunology* Humans NF-kappa B / physiology* Tumor Necrosis Factor-alpha / physiology* |
| Chemical | |
Reg. No./Substance:
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0/NF-kappa B; 0/Tumor Necrosis Factor-alpha |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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