Document Detail


Hepatitis B virus infection and the risk of male infertility: a population-based analysis.
MedLine Citation:
PMID:  25439807     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the risk of male infertility among patients with hepatitis B virus (HBV) infection.
DESIGN: A nationwide, population-based cohort study.
SETTING: Not applicable.
PATIENT(S): Men infected with HBV (n = 5,138) and men without HBV infection (n = 25,690).
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Male infertility, as defined by the International Classification of Diseases, Ninth Revision, Clinical Modification.
RESULT(S): The incidence of infertility was 1.59 times higher in patients with HBV infection than in those without HBV infection (2.21 vs. 1.39 per 1,000 person-years). The risk of developing infertility remained significant among patients with HBV infection (hazard ratio 1.52, 95% confidence interval 1.20-1.92) after adjusting for covariates in a multivariate Cox proportional hazards model.
CONCLUSION(S): The data show an increased incidence and risk of infertility among men with HBV infection compared with men without HBV.
Authors:
Fu-Hsiung Su; Shih-Ni Chang; Fung-Chang Sung; Chien-Tien Su; Ying-Hua Shieh; Cheng-Chieh Lin; Chih-Ching Yeh
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Publication Detail:
Type:  Journal Article     Date:  2014-10-22
Journal Detail:
Title:  Fertility and sterility     Volume:  102     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-12-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1677-84     Citation Subset:  IM    
Copyright Information:
Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
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