| Hepatitis B virus infection in pregnant mothers and its transmission to infants. | |
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MedLine Citation:
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PMID: 1452257 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Screening for serological markers of hepatitis B virus infection was done on 500 pregnant mothers. HBsAg, AntiHBs and HBeAg were done. HBsAg was positive in 3.6%, AntiHBs in 17.4% and HBeAg in 0.4% cases. The infants born to the asymptomatic HBsAg carrier mothers were followed up to 6 months to determine the vertical transmission of HBV infection. Rate of transmission of infection from HBsAg positive mothers to infants were 16.66% irrespective of HBeAg status, whereas it was nearly 100% in case of HBeAg positive mothers. All of the HBsAg positive infants developed the antigenemia between 3-6 months of age, supporting the hypothesis that intrapartum transmission is the major mode of vertical transmission. |
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Authors:
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S Akhter; M Q Talukder; N Bhuiyan; T A Chowdhury; M N Islam; S Begum |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of pediatrics Volume: 59 ISSN: 0019-5456 ISO Abbreviation: Indian J Pediatr Publication Date: 1992 Jul-Aug |
Date Detail:
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Created Date: 1992-12-31 Completed Date: 1992-12-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0417442 Medline TA: Indian J Pediatr Country: INDIA |
Other Details:
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Languages: eng Pagination: 411-5 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, IPGM & R, Dhaka, Bangla Desh. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Hepatitis B / diagnosis, transmission* Hepatitis B Surface Antigens / analysis Humans India Infant Infant, Newborn Maternal-Fetal Exchange / physiology* Pregnancy Pregnancy Complications, Infectious / diagnosis* Risk Factors Water Microbiology |
| Chemical | |
Reg. No./Substance:
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0/Hepatitis B Surface Antigens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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