Document Detail

Hepatitis B virus infection in pregnant mothers and its transmission to infants.
MedLine Citation:
PMID:  1452257     Owner:  NLM     Status:  MEDLINE    
Screening for serological markers of hepatitis B virus infection was done on 500 pregnant mothers. HBsAg, AntiHBs and HBeAg were done. HBsAg was positive in 3.6%, AntiHBs in 17.4% and HBeAg in 0.4% cases. The infants born to the asymptomatic HBsAg carrier mothers were followed up to 6 months to determine the vertical transmission of HBV infection. Rate of transmission of infection from HBsAg positive mothers to infants were 16.66% irrespective of HBeAg status, whereas it was nearly 100% in case of HBeAg positive mothers. All of the HBsAg positive infants developed the antigenemia between 3-6 months of age, supporting the hypothesis that intrapartum transmission is the major mode of vertical transmission.
S Akhter; M Q Talukder; N Bhuiyan; T A Chowdhury; M N Islam; S Begum
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  59     ISSN:  0019-5456     ISO Abbreviation:  Indian J Pediatr     Publication Date:    1992 Jul-Aug
Date Detail:
Created Date:  1992-12-31     Completed Date:  1992-12-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  411-5     Citation Subset:  IM    
Department of Pediatrics, IPGM & R, Dhaka, Bangla Desh.
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MeSH Terms
Hepatitis B / diagnosis,  transmission*
Hepatitis B Surface Antigens / analysis
Infant, Newborn
Maternal-Fetal Exchange / physiology*
Pregnancy Complications, Infectious / diagnosis*
Risk Factors
Water Microbiology
Reg. No./Substance:
0/Hepatitis B Surface Antigens

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