Document Detail

Hepatic ultrasonography and pathological findings in dogs with hepatocutaneous syndrome: new concepts.
MedLine Citation:
PMID:  8558487     Owner:  NLM     Status:  MEDLINE    
In dogs, hepatocutaneous syndrome (superficial necrolytic dermatitis) belongs to a group of syndromes in which cutaneous signs signal the presence of systemic disease. It is characterized by parakeratosis, superficial necrolysis, and basilar hyperplasia of the epidermis, in association with an unusual hepatopathy accompanied by certain metabolic derangements. Hepatocutaneous syndrome was diagnosed in 3 dogs on the basis of typical dermatologic changes and clinicopathologic findings. Hepatic ultrasonography revealed a hyperechoic network surrounding hypoechoic areas of parenchyma, resulting in a Swiss cheese-like appearance. The ultrasonographic image corresponded to the pathological findings. The liver had a nodular appearance, both grossly and microscopically; this was attributed to collapse of the areas of parenchyma surrounding the nodules, rather than to the cirrhosis and/or nodular hyperplasia reported previously.
L S Jacobson; R M Kirberger; J W Nesbit
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of veterinary internal medicine / American College of Veterinary Internal Medicine     Volume:  9     ISSN:  0891-6640     ISO Abbreviation:  J. Vet. Intern. Med.     Publication Date:    1995 Nov-Dec
Date Detail:
Created Date:  1996-02-28     Completed Date:  1996-02-28     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8708660     Medline TA:  J Vet Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  399-404     Citation Subset:  IM    
Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
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MeSH Terms
Dermatitis / complications,  pathology,  ultrasonography,  veterinary*
Dog Diseases / pathology*,  therapy,  ultrasonography
Liver / pathology
Liver Diseases / complications,  pathology,  ultrasonography,  veterinary*
Necrosis / veterinary
Pancreas / pathology
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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