| Hepatic metastatic thymoma and myasthenia gravis twenty-two years after the apparent cure of an invasive thymoma. A case report and review of the literature. | |
| | |
MedLine Citation:
|
PMID: 3537213 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report the case of a 62-year-old woman who presented in myasthenic crisis 22 years after radiation- and chemotherapy of an invasive thymoma which occurred during pregnancy. There was no evidence of recurrence of the thymoma at its original site, but an isolated hepatic metastasis was discovered. Biopsy of the mass revealed a spindle cell thymoma, whereas the original histology was that of a mixed round and spindle cell thymoma with moderate lymphocytic infiltration. The patient expired in spite of treatment with steroids, pyridostigmine bromide and plasma exchange on the one hand and cyclophosphamide with adriamycin on the other. To our knowledge, 22 years is the longest reported interval for the appearance of metastatic thymoma and myasthenia gravis after the diagnosis and apparent cure of a primary thymoma. This is also the only reported case of thymoma occurring during pregnancy but not associated with a rapidly fatal outcome. |
| | |
Authors:
|
M A Denayer; K R Rao; D Wirz; D McNally |
Related Documents
:
|
11549933 - Coexistence of delusions of pregnancy and infestation in a male. 16246423 - Legionella pneumophila pneumonia during pregnancy: a case report. 9191073 - Differential proopiomelanocortin gene expression in the medial basal hypothalamus of ra... |
Publication Detail:
|
Type: Case Reports; Journal Article; Review |
Journal Detail:
|
Title: Journal of the neurological sciences Volume: 76 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 1986 Nov |
Date Detail:
|
Created Date: 1987-01-14 Completed Date: 1987-01-14 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 23-30 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Humans Liver Neoplasms / complications, pathology, secondary* Middle Aged Myasthenia Gravis / complications* Pregnancy Pregnancy Complications, Neoplastic / pathology Thymoma / complications, pathology, secondary* Thymus Neoplasms / complications* Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Problems arising during chronic treatment with L-dopa for Parkinson's disease: changes in response t...
Next Document: Twice-daily nicardipine in the treatment of essential hypertension.