Document Detail


Hepatic intra-arterial lipiodol ultrasound guided biopsy in the management of hepatocellular carcinoma.
MedLine Citation:
PMID:  8252199     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One hundred and fifty-one consecutive new patients with suspected hepatocellular carcinoma (HCC) were investigated from 1989 to 1990. Ultrasound showed the tumours to be inoperable in 111 patients. Selective hepatic angiography revealed 17 more patients with inoperable HCC. Hepatic intra-arterial lipiodol (HIAL) was injected in the remaining 23 patients. In 16 of them, a clinical decision could be reached basing on the radiological findings. Hepatic intra-arterial lipiodol ultrasound (HIAL/USG) guided biopsy was done in seven patients with suspicious lesions. Histology obtained with this method revealed hyperplastic cirrhotic nodules in four patients (two with suspected HCC and two with suspected secondaries). In another two patients, the suspected lesions were confirmed to be malignant. In the last patient who had received chemotherapy for extensive HCC, HIAL/USG guided biopsy revealed necrotic tissue only. At laparotomy, diffuse infiltrative abnormality was found and repeated biopsy confirmed residual malignancy in the necrotic tumour. We conclude that when there is radiological uncertainty as to the nature and extent of the HCC, HIAL/USG guided biopsy can help the clinician to make important decisions.
Authors:
W Y Lau; M Arnold; N W Leung; T W Leung; M Chan; W Shiu; C Metreweli; A K Li
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgical oncology     Volume:  2     ISSN:  0960-7404     ISO Abbreviation:  Surg Oncol     Publication Date:  1993  
Date Detail:
Created Date:  1994-01-11     Completed Date:  1994-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9208188     Medline TA:  Surg Oncol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  119-24     Citation Subset:  IM    
Affiliation:
Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Biopsy / methods
Carcinoma, Hepatocellular / pathology*,  surgery,  ultrasonography
Female
Humans
Iodized Oil / administration & dosage
Liver Neoplasms / pathology*,  surgery,  ultrasonography
Male
Middle Aged
Chemical
Reg. No./Substance:
8001-40-9/Iodized Oil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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