Document Detail

Heparinization of alimentation solutions administered through peripheral veins in premature infants: a controlled study.
MedLine Citation:
PMID:  6433319     Owner:  NLM     Status:  MEDLINE    
A randomized controlled study was done to determine whether the addition of heparin (1 U/mL) to peripheral intravenous alimentation solutions would affect the incidence of phlebitis and duration of patency of intravenous catheters in premature infants. Twenty-two-gauge Teflon catheters were uniformly used. One hundred five catheters infused with heparin were placed in 13 infants, and 122 catheters were placed in the control group of 13 infants. The time, nature, and incidence of complications were noted for each infusion site. Infusion of heparin was found to double the duration of patency of intravenous catheters and to reduce significantly the incidence of phlebitis. No complications related to the administration of heparin were noted. Heparinization of intravenous alimentation solutions should therefore be considered in premature infants as a means of reducing the work load and incidence of complications associated with peripheral lines.
G Alpan; F Eyal; C Springer; B Glick; K Goder; J Armon
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Pediatrics     Volume:  74     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-10-03     Completed Date:  1984-10-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  375-8     Citation Subset:  AIM; IM    
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MeSH Terms
Clinical Trials as Topic
Heparin / therapeutic use*
Infant, Newborn
Infant, Premature, Diseases / prevention & control*
Parenteral Nutrition*
Parenteral Nutrition, Total*
Phlebitis / prevention & control*
Random Allocation
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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