| Heparin for pregnant women with acquired or inherited thrombophilias. | |
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MedLine Citation:
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PMID: 12804477 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Thrombophilias, which are associated with a predisposition to thrombotic events, have been implicated in adverse obstetrical outcomes such as intrauterine growth restriction, stillbirth, severe early onset pre-eclampsia, and placental abruption. Heparin administration in pregnancy may reduce the risk of these events. OBJECTIVES: The objective of this review was to assess the effects of heparin on pregnancy outcomes for women with a thrombophilia. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register (July 2002), MEDLINE, EMBASE, CINAHL, Scidex (via OVID Technologies - July 2002) and reference lists and personal files. SELECTION CRITERIA: Randomized controlled trials comparing heparin with placebo or no treatment, or randomized controlled trials comparing any two treatments. Quasi randomized studies would be included. DATA COLLECTION AND ANALYSIS: Data would be abstracted from identified studies and recorded on a paper form by two reviewers. MAIN RESULTS: No studies were included. REVIEWER'S CONCLUSIONS: There are no completed trials to determine the effects of heparin on pregnancy outcomes for women with a thrombophilia. |
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Authors:
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M C Walker; S E Ferguson; V M Allen |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cochrane database of systematic reviews (Online) Volume: - ISSN: 1469-493X ISO Abbreviation: Cochrane Database Syst Rev Publication Date: 2003 |
Date Detail:
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Created Date: 2003-06-13 Completed Date: 2003-07-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 100909747 Medline TA: Cochrane Database Syst Rev Country: England |
Other Details:
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Languages: eng Pagination: CD003580 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada, K1H 8L6. mwalker99@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anticoagulants
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therapeutic use* Female Heparin / therapeutic use* Humans Pregnancy Pregnancy Complications, Hematologic / drug therapy* Thrombophilia / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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