| Heparin-induced thrombocytopenia and thrombosis syndrome after cardiac surgery. | |
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MedLine Citation:
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PMID: 15051266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case report of multisystem organ failure and limb loss associated with coronary artery bypass is reported. Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) occurs in 1% to 2% of patients suffering from thrombocytopenia associated with heparin or heparinoid use, which amounts to less than 1.4% of the cardiac surgical population. It carries a risk of significant comorbidity and mortality. Providers involved in the care of such patients should be well versed in the etiology and potential complications of HITTS, the treatment options, and alternative modalities of anticoagulation available for use. |
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Authors:
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Joseph DuBose; Michael Sutherland; Michael Moulton; Bhaktan Krishnan; Jerry Cohn; Jerry W Pratt |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Current surgery Volume: 61 ISSN: 0149-7944 ISO Abbreviation: Curr Surg Publication Date: 2004 Mar-Apr |
Date Detail:
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Created Date: 2004-03-30 Completed Date: 2004-07-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802123 Medline TA: Curr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 209-12 Citation Subset: IM |
Affiliation:
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Department of Surgery, Keesler Medical Center, Keesler Air Force Base, Suite 1A132, 301 Fisher Street, MS 30534, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amputation Anticoagulants / adverse effects* Aortic Valve Stenosis / diagnosis, surgery Cecum / blood supply Colectomy Combined Modality Therapy Coronary Artery Bypass / adverse effects* Enzyme-Linked Immunosorbent Assay Flow Cytometry Heparin / adverse effects* Hirudin Therapy Humans Ileostomy Ischemia / diagnosis, epidemiology, etiology, therapy Leg / blood supply Male Middle Aged Platelet Aggregation Platelet Count Risk Factors Syndrome Thrombocytopenia / blood, diagnosis, etiology*, therapy Thrombosis / blood, diagnosis, etiology*, therapy |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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