Document Detail

Heparin-induced thrombocytopenia and extracorporeal membrane oxygenation: a case report and review of the literature.
MedLine Citation:
PMID:  21449228     Owner:  NLM     Status:  In-Process    
Heparin-induced thrombocytopenia (HIT) is an immune-mediated coagulation side effect of heparin therapy characterized by thrombocytopenia and by a paradoxical prothrombotic state following heparin exposure when thrombotic or thromboembolic events accurse, the condition is classified as Heparin-induced thrombocytopenia with thrombosis (HITT). We report a case of HITT with evidence of small-vessel arterial thrombosis in a 5-day-old newborn receiving extracorporeal membrane oxygenation (ECMO) for congenital diaphragmatic hernia, and our attempt of bivalirudin alternative treatment. We also review previous reports regarding HIT and ECMO with the alternative management in this unique population.
Uri Pollak; Joanne Yacobobich; Hannah Tamary; Ovdi Dagan; Orit Manor-Shulman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of extra-corporeal technology     Volume:  43     ISSN:  0022-1058     ISO Abbreviation:  J Extra Corpor Technol     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0267637     Medline TA:  J Extra Corpor Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5-12     Citation Subset:  T    
Cardiac Intensive Care Unit, Schneider Children's Medical Center of Israel, Petah Tiqwa, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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