| Heparin-induced spinal fractures. | |
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MedLine Citation:
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PMID: 439319 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 27-year-old woman received heparin sodium for 152 days because of antepartum iliofemoral thrombophlebitis. At the end of this time, spinal osteoporosis and multiple vertebral fractures became clinically evident and were attributed to the prolonged administration of heparin. Previously reported cases of "heparin osteoporosis" were reviewed. The significance of the daily dose of heparin and the duration of therapy are reemphasized. This therapeutic complication and the management of antepartum iliofemoral thrombophlebitis are discussed. Prolonged administration of heparin in daily doses exceeding 10,000 units is potentially hazardous. |
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Authors:
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J W Squires; L W Pinch |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: JAMA : the journal of the American Medical Association Volume: 241 ISSN: 0098-7484 ISO Abbreviation: JAMA Publication Date: 1979 Jun |
Date Detail:
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Created Date: 1979-07-28 Completed Date: 1979-07-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7501160 Medline TA: JAMA Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2417-8 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Fractures, Spontaneous / chemically induced* Heparin / therapeutic use Humans Lumbar Vertebrae / injuries Osteoporosis / chemically induced* Pregnancy Pregnancy Complications, Cardiovascular* Spinal Injuries / chemically induced* Thoracic Vertebrae / injuries Thrombophlebitis / drug therapy Time Factors |
| Chemical | |
Reg. No./Substance:
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9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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