Document Detail

Heparin-induced cardiac tamponade and life-threatening hyperkalema in a patient with chronic hemodialysis.
MedLine Citation:
PMID:  15875438     Owner:  NLM     Status:  MEDLINE    
Heparin, a commonly used anticoagulant agent, is frequently used in patients undergoing hemodialysis. As with most medications, heparin has a significant side effect profile. Two of its most important side effects, major bleeding and hyperkalemia, may be devastating without immediate diagnosis and treatment. Major bleeding such as gastrointestinal, genitourinary or intracranial bleeding is occasionally encountered and rarely neglected. However, heparin-induced cardiac tamponade is rarely encountered and may be easily overlooked. Another side effect, heparin-induced hyperkalemia, an unusual but well-described side effect, is frequently forgotten until life-threatening arrhythmia has occurred. We report a case involving a 40-year-old male patient with uremia, who had received heparin for 10 days for deep vein thrombosis in the left lower extremity. Hemopericardium with cardiac tamponade and life-threatening hyperkalemia were both noted in this patient.
Ho-Ming Su; Wen-Chol Voon; Chih-Sheng Chu; Tsung-Hsien Lin; Wen-Ter Lai; Sheng-Hsiung Sheu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Kaohsiung journal of medical sciences     Volume:  21     ISSN:  1607-551X     ISO Abbreviation:  Kaohsiung J. Med. Sci.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-05-06     Completed Date:  2005-06-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100960562     Medline TA:  Kaohsiung J Med Sci     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  128-33     Citation Subset:  IM    
Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
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MeSH Terms
Anticoagulants / adverse effects,  therapeutic use
Cardiac Tamponade / chemically induced*,  therapy
Heart / drug effects,  physiopathology
Heparin / adverse effects*,  therapeutic use
Hyperkalemia / chemically induced*,  therapy
Renal Dialysis*
Venous Thrombosis / drug therapy
Reg. No./Substance:
0/Anticoagulants; 9005-49-6/Heparin

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