| Heparin does not reduce catheter sepsis during total parenteral nutrition. | |
| | |
MedLine Citation:
|
PMID: 3925179 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Although it is recognized that the addition of heparin to total parenteral nutrition solutions reduces subclavian vein thrombosis from percutaneous polyethylene catheters, it does not affect the low thrombosis rate associated with polyurethane catheters. It has been suggested that heparin also reduces catheter sepsis during total parenteral nutrition. We reviewed the sepsis rate in 86 patients randomized to receive iv nutrition with or without heparin through polyethylene, polyvinyl, and polyurethane catheters. Blood was drawn from febrile patients for culture; if positive, catheters were removed and the tips cultured. Catheters were considered infected if blood and catheter tips were positive, or if fever disappeared within 48 hr after catheter removal, even if cultures were negative. Catheter sepsis occurred in two patients in both groups. It appears that heparin does not reduce sepsis from percutaneous subclavian vein catheters. Although its use may be indicated to reduce thrombosis associated with polyethylene catheters, there is no indication for its use to reduce sepsis with either type of catheter. |
| | |
Authors:
|
K A Kudsk; C Powell; J M Mirtallo; P J Fabri; R L Ruberg |
Related Documents
:
|
15851219 - Successful release of entrapped circumferential mapping catheters in patients undergoin... 22477649 - Critical hand ischaemia after transradial cardiac catheterisation: an uncommon complica... 22472849 - A 'clover' coronary artery: role of coronary computed tomography to indicate optimal tr... 22378479 - Initial experience in evaluating the prevalence of unruptured intracranial aneurysms de... 8368659 - Avoiding complications of long-term venous access. 22675159 - Aortic coarctations and coronary artery disease: the xy factor. 11399579 - Haemostasis and thrombosis: current clinical practice: low-molecular-weight heparins in... 17693439 - Recurrent endocarditis of a bicuspid aortic valve due to q fever. 14739309 - Value of transcatheter arterial embolization with coils and n-butyl cyanoacrylate for l... |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: JPEN. Journal of parenteral and enteral nutrition Volume: 9 ISSN: 0148-6071 ISO Abbreviation: JPEN J Parenter Enteral Nutr Publication Date: 1985 May-Jun |
Date Detail:
|
Created Date: 1985-08-14 Completed Date: 1985-08-14 Revised Date: 2007-02-21 |
Medline Journal Info:
|
Nlm Unique ID: 7804134 Medline TA: JPEN J Parenter Enteral Nutr Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 348-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bacterial Infections
/
prevention & control* Catheterization / adverse effects* Heparin / administration & dosage* Humans Parenteral Nutrition* Parenteral Nutrition, Total* Prospective Studies |
| Chemical | |
Reg. No./Substance:
|
9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nutritional evaluation and supplementation of elderly subjects participating in a "meals on wheels" ...
Next Document: Noninvasive outpatient nutritional therapy in inflammatory bowel disease.