Document Detail

Heparin-bonded circuit with low systemic anticoagulation in a patient with heparin-induced thrombocytopenia: a case report.
MedLine Citation:
PMID:  10847957     Owner:  NLM     Status:  MEDLINE    
Heparin-induced thrombocytopenia (HIT) in patients undergoing open heart surgery has been reported with increasing frequency. Several strategies have been suggested to approach this difficult problem. However, the syndrome is still associated with significant morbidity and mortality. We describe an 82-year-old male with HIT who underwent coronary artery bypass grafting utilizing a heparin-bonded cardiopulmonary bypass circuit with very low systemic anticoagulation. Only one unit of packed red blood cells was transfused. The patient recovered uneventfully. This strategy is safe and effective, and, therefore, should be considered in patients with HIT.
P J O'Gara; G S Aldea; R J Shemin; O M Shapira
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of extra-corporeal technology     Volume:  31     ISSN:  0022-1058     ISO Abbreviation:  J Extra Corpor Technol     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2000-04-28     Completed Date:  2000-04-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0267637     Medline TA:  J Extra Corpor Technol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  142-4     Citation Subset:  T    
Department of Cardiothoracic Surgery, Boston Medical Center, MA 02118, USA.
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MeSH Terms
Aged, 80 and over
Anticoagulants / adverse effects*
Cardiopulmonary Bypass / instrumentation*
Heparin / adverse effects*
Thrombocytopenia / chemically induced*
Reg. No./Substance:
0/Anticoagulants; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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