| Heparin after angioplasty: an unresolved issue? | |
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MedLine Citation:
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PMID: 8299638 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Restenosis following coronary angioplasty remains a significant problem. Experimental work suggests that appropriate use of heparin may be beneficial through inhibition of smooth muscle cell proliferation. Possible mechanisms of this effect in various models, are discussed. Limited clinical studies to date, however, have failed to show therapeutic efficacy. Possible reasons for this lack of effect are discussed and the importance of assessing heparin in appropriate clinical trials is emphasized. |
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Authors:
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R S More; M J Brack; A H Gershlick |
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Publication Detail:
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Type: In Vitro; Journal Article; Review |
Journal Detail:
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Title: European heart journal Volume: 14 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1993 Nov |
Date Detail:
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Created Date: 1994-03-04 Completed Date: 1994-03-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1543-7 Citation Subset: IM |
Affiliation:
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Academic Department of Cardiology, Glenfield General Hospital, Leicester, U.K. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary* Animals Heparin / therapeutic use* Humans Postoperative Care |
| Chemical | |
Reg. No./Substance:
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9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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