Document Detail

Henoch-Schönlein purpura in rheumatoid arthritis.
MedLine Citation:
PMID:  7932429     Owner:  NLM     Status:  MEDLINE    
This is the first report of Henoch-Schönlein purpura associated with permanent joint damage due to rheumatoid arthritis, which was observed in 3 of the 10 adults we treated for Henoch-Schönlein purpura since 1974. Each of 3 women had been admitted with palpable purpura of the lower extremities. The diagnosis was based on various findings including arthralgia, stiffness, and/or swelling of the joints, and on the results of radiographic, immunofluorescence and other studies. Renal biopsy revealed slight mesangial proliferation in 2 of the patients. The nephropathy did not deteriorate following discharge. However, bilateral swelling of the wrists with destructive joint changes was subsequently observed on radiographs in all patients. Since 2 patients showed positivity for human leukocyte antigen DR4, this antigen may have been a genetic factor in the joint disease in these patients.
H Mitsuhashi; M Mitsuhashi; Y Tsukada; S Yano; T Naruse
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  21     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1994 Jun 
Date Detail:
Created Date:  1994-10-25     Completed Date:  1994-10-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1138-40     Citation Subset:  IM    
Third Department of Internal Medicine, Gunma University School of Medicine, Japan.
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MeSH Terms
Arthritis, Rheumatoid / complications*,  drug therapy,  radiography
Prednisolone / therapeutic use
Purpura, Schoenlein-Henoch / etiology*,  pathology
Wrist Joint / radiography
Reg. No./Substance:

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