Document Detail

Hemostatic changes associated with normal and abnormal pregnancies.
MedLine Citation:
PMID:  11586509     Owner:  NLM     Status:  MEDLINE    
Routine hemostatic laboratory tests lack sensitivity and are of little value in the detection of the pregnancy associated hypercoagulable conditions. Assays for F 1 + 2, AT levels, TAT complex, APC activity, FPA, D-Dimers, tPA, plasminogen, PAI 1, and PAI 2 are more specific for fibrin formation and lysis. Monitoring these tests along with fibrinogen and platelet counts provides important information for the early detection of hemostatic activation and for monitoring the severity of the condition. Early detection and therapy is essential for limiting the deleterious complications of pregnancy. Advances in research, the development of new tests such as the TM assay and gene analysis, as well as highly skilled personnel, are required for the providing of quality pre and postnatal healthcare.
G L Davis
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical laboratory science : journal of the American Society for Medical Technology     Volume:  13     ISSN:  0894-959X     ISO Abbreviation:  Clin Lab Sci     Publication Date:  2000  
Date Detail:
Created Date:  2001-10-05     Completed Date:  2001-10-18     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8806547     Medline TA:  Clin Lab Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  223-8     Citation Subset:  T    
322 N Kedzie Lab, Michigan State University, E Lansing, MI 48824, USA.
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MeSH Terms
Blood Coagulation Tests
Hematologic Tests
Pregnancy / blood*
Pregnancy Complications, Hematologic / blood*,  diagnosis
Risk Factors
Thrombosis / blood,  diagnosis

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