| Hemostatic changes associated with normal and abnormal pregnancies. | |
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MedLine Citation:
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PMID: 11586509 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Routine hemostatic laboratory tests lack sensitivity and are of little value in the detection of the pregnancy associated hypercoagulable conditions. Assays for F 1 + 2, AT levels, TAT complex, APC activity, FPA, D-Dimers, tPA, plasminogen, PAI 1, and PAI 2 are more specific for fibrin formation and lysis. Monitoring these tests along with fibrinogen and platelet counts provides important information for the early detection of hemostatic activation and for monitoring the severity of the condition. Early detection and therapy is essential for limiting the deleterious complications of pregnancy. Advances in research, the development of new tests such as the TM assay and gene analysis, as well as highly skilled personnel, are required for the providing of quality pre and postnatal healthcare. |
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Authors:
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G L Davis |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinical laboratory science : journal of the American Society for Medical Technology Volume: 13 ISSN: 0894-959X ISO Abbreviation: Clin Lab Sci Publication Date: 2000 |
Date Detail:
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Created Date: 2001-10-05 Completed Date: 2001-10-18 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8806547 Medline TA: Clin Lab Sci Country: United States |
Other Details:
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Languages: eng Pagination: 223-8 Citation Subset: T |
Affiliation:
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322 N Kedzie Lab, Michigan State University, E Lansing, MI 48824, USA. Davis@pilot.msu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Coagulation Tests Female Hematologic Tests Hemostasis* Humans Pregnancy / blood* Pregnancy Complications, Hematologic / blood*, diagnosis Risk Factors Thrombosis / blood, diagnosis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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