Document Detail

Hemorrhagic retinopathy as the presenting manifestation of sarcoidosis.
MedLine Citation:
PMID:  8594636     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The diagnosis of ocular sarcoidosis is particularly challenging in patients who present with atypical clinical findings and no evidence of systemic disease. We describe a patient whose initial clinical manifestation of sarcoidosis was a unilateral hemorrhagic retinopathy. METHOD: Clinicopathologic case study. RESULTS: The diagnosis of sarcoidosis in this patient was delayed for over a year principally because of the atypical retinal findings and because repeated chest X-rays and serum angiotensin covering enzyme (ACE) levels were normal. Surgical enucleation of the eye once it was blind revealed a large noncaseating granuloma of the ciliary body. Inflammation and thrombosis of several large caliber retinal veins and a single branch of the retrolaminar hemicentral retinal vein were found. CONCLUSIONS: Major retinal branch vein occlusion and hemi-central retinal branch occlusion are rare complications of ocular sarcoidosis. Normal serum ACE levels do not exclude the diagnosis of ocular sarcoidosis even in patients with considerable amounts of intraocular granulomatous inflammation.
A J DeRosa; C E Margo; M E Orlick
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Retina (Philadelphia, Pa.)     Volume:  15     ISSN:  0275-004X     ISO Abbreviation:  Retina (Philadelphia, Pa.)     Publication Date:  1995  
Date Detail:
Created Date:  1996-04-09     Completed Date:  1996-04-09     Revised Date:  2006-12-15    
Medline Journal Info:
Nlm Unique ID:  8309919     Medline TA:  Retina     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  422-7     Citation Subset:  IM    
Department of Ophthalmology, University of South Florida College of Medicine, Tampa, USA.
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MeSH Terms
Choroid / pathology
Fundus Oculi
Retina / pathology
Retinal Diseases / complications,  diagnosis*,  pathology
Retinal Hemorrhage / diagnosis*,  etiology,  pathology
Retinal Vessels / pathology
Sarcoidosis / complications,  diagnosis*,  pathology
Comment In:
Retina. 1996;16(3):266-7   [PMID:  8789873 ]

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