Document Detail

Hemorrhagic diathesis as the presenting symptom of neonatal cholestasis.
MedLine Citation:
PMID:  25349836     Owner:  NLM     Status:  PubMed-not-MEDLINE    
A 4-week-old infant presented with a coagulation disorder resulting from a vitamin K deficiency. The vitamin K deficiency was caused by neonatal cholestasis due to biliary atresia. Jaundice, hepatomegaly and pale stools are the predominant presenting symptoms of biliary atresia, none of which were recognized in our patient before admission. However, the patient presented with bleeding caused by vitamin K deficiency. She was fully breastfed and had received adequate doses of vitamin K at birth and from the age of 1 week. In case of a hemorrhagic diathesis due to neonatal cholestasis, timely identification of treatable underlying disorders, in particular biliary atresia, is important because an early surgical intervention results in a better prognosis. Meticulous history taking and a thorough physical exam can be decisive for an early diagnosis and subsequent intervention.
Liesbeth Claire Faverey; Yvan Vandenplas
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Publication Detail:
Type:  Journal Article     Date:  2014-09-30
Journal Detail:
Title:  Pediatric gastroenterology, hepatology & nutrition     Volume:  17     ISSN:  2234-8646     ISO Abbreviation:  Pediatr Gastroenterol Hepatol Nutr     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-10-28     Completed Date:  2014-10-28     Revised Date:  2014-10-30    
Medline Journal Info:
Nlm Unique ID:  101590471     Medline TA:  Pediatr Gastroenterol Hepatol Nutr     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  191-5     Citation Subset:  -    
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