Document Detail

Hemorrhage involving the upper airway in hemophilia.
MedLine Citation:
PMID:  3742923     Owner:  NLM     Status:  MEDLINE    
Bleeding involving the upper airway is a rare, highly emergent complication of hemophilia. This report describes the occurrence of two distinct episodes in a patient with severe factor IX deficiency. Clinical data from other cases described in the literature is summarized with regard to predisposing factors, age of incidence, presenting symptomatology, diagnosis, and management. Pertinent features of this bleeding complication include: high prevalence involving the pediatric population, presentation with non-specific symptoms (e.g., sore throat, dysphagia) early in the course of the bleeding episode, progression to complete upper respiratory obstruction if not recognized and treated, and the need for relatively high levels of the deficient coagulation factor for a period of at least 7 days to ensure resolution of the hematoma. The diagnosis is confirmed by observing retropharyngeal soft-tissue widening on lateral neck x-ray or alternatively, via cervical computed tomography.
G Bray; D Nugent
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  25     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-09-29     Completed Date:  1986-09-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  436-9     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Hemophilia B / complications*
Hemorrhage / etiology*,  radiography
Pharyngeal Diseases / etiology*,  radiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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