Document Detail


Hemorheological changes caused by intermittent Pringle (Baron) maneuver in beagle canine model.
MedLine Citation:
PMID:  19029643     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In liver resection operations the Pringle (Baron) maneuver can be used for temporary ischemia by clamping the hepatoduodenal ligament intermittently. In this beagle canine model we investigated whether hemorheological parameters may alter in systemic, portal and hepatic venous blood and in arterial samples during-after Pringle maneuvers. In Pringle Group unilateral femoral artery and external jugular vein were cannulated. From median laparotomy the hepatoduodenal ligament was exposed. The portal venous system was catheterized via a mesenteric vein and through the inferior caval vein a catheter was led to the hepatic veins. After stabilization, a 15-minute Pringle maneuver was carried out three times with 5-minute interpolated reperfusion periods. In Control Group Pringle maneuvers were not made. Before and after Pringle maneuvers parallel blood samples were taken from the cannulated vessels for determining hematological parameters and erythrocyte aggregation. Following Pringle maneuvers erythrocyte deformability, blood and plasma viscosity were also tested. The results showed that besides systemic hemorheological effects of the intermittent Pringle maneuver local leukocyte count, hematocrit and erythrocyte aggregation index altered mainly in portal venous blood, depending on the repeating number of the maneuvers. Thus, investigations of hemorheological parameters might be useful to determine the optimal duration of the Pringle maneuver.
Authors:
A Furka; N Nemeth; A Gulyas; E Brath; K Peto; I E Takacs; I Furka; P Sapy; I Miko
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical hemorheology and microcirculation     Volume:  40     ISSN:  1386-0291     ISO Abbreviation:  Clin. Hemorheol. Microcirc.     Publication Date:  2008  
Date Detail:
Created Date:  2008-11-25     Completed Date:  2009-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9709206     Medline TA:  Clin Hemorheol Microcirc     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  177-89     Citation Subset:  IM    
Affiliation:
Institute of Surgery, Department of Operative Techniques and Surgical Research, Medical and Health Science Centre, Faculty of Medicine, University of Debrecen, Hungary.
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Erythrocyte Aggregation*
Humans
Laparotomy / methods*
Leukocyte Count
Liver / metabolism,  surgery*
Male
Models, Biological*
Portal Vein / metabolism,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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