Document Detail

Hemorheological alterations in mild essential hypertension.
MedLine Citation:
PMID:  1412193     Owner:  NLM     Status:  MEDLINE    
Blood rheological properties were studied in 21 patients suffering from essential hypertension (EHT), degree I-II according to WHO criteria. These patients were diagnosed "de novo". The whole blood filterability (WBF), blood viscosity (BV) at 230 s-1 and 23 s-1, red cell deformability (FI), erythrocyte aggregation in autologous (MEA) and normal plasma (MEAc), fibrinogen (Fbg) and hematocrit (Ht) have been evaluated. In the hypertensive patients we have found decreased WBF, greater BV and FI in comparison with the control group (p less than 0.001). Likewise, MEA and Fbg were increased, though the differences were less significant (p less than 0.01). The evaluation of Ht did not show any differences between the two groups. The results suggest that in the newly diagnosed EHT, clear hemorheological alterations occur, both in plasma and in the erythrocytes, which could play a role in the pathogenesis of the aforementioned disease.
A Vayá; M Martínez; J Garcia; M Labios; J Aznar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Thrombosis research     Volume:  66     ISSN:  0049-3848     ISO Abbreviation:  Thromb. Res.     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-10-30     Completed Date:  1992-10-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0326377     Medline TA:  Thromb Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  223-9     Citation Subset:  IM    
Department of Clinical Pathology, Hospital La Fe, Valencia, Spain.
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MeSH Terms
Blood Cell Count
Blood Viscosity*
Erythrocyte Aggregation*
Erythrocyte Deformability*
Erythrocyte Indices
Fibrinogen / analysis*
Hypertension / blood*
Middle Aged
Vascular Resistance
Reg. No./Substance:
Erratum In:
Thromb Res 1993 Dec 1;72(5):473

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