| Hemorheological alterations in mild essential hypertension. | |
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MedLine Citation:
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PMID: 1412193 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Blood rheological properties were studied in 21 patients suffering from essential hypertension (EHT), degree I-II according to WHO criteria. These patients were diagnosed "de novo". The whole blood filterability (WBF), blood viscosity (BV) at 230 s-1 and 23 s-1, red cell deformability (FI), erythrocyte aggregation in autologous (MEA) and normal plasma (MEAc), fibrinogen (Fbg) and hematocrit (Ht) have been evaluated. In the hypertensive patients we have found decreased WBF, greater BV and FI in comparison with the control group (p less than 0.001). Likewise, MEA and Fbg were increased, though the differences were less significant (p less than 0.01). The evaluation of Ht did not show any differences between the two groups. The results suggest that in the newly diagnosed EHT, clear hemorheological alterations occur, both in plasma and in the erythrocytes, which could play a role in the pathogenesis of the aforementioned disease. |
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Authors:
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A Vayá; M Martínez; J Garcia; M Labios; J Aznar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Thrombosis research Volume: 66 ISSN: 0049-3848 ISO Abbreviation: Thromb. Res. Publication Date: 1992 May |
Date Detail:
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Created Date: 1992-10-30 Completed Date: 1992-10-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0326377 Medline TA: Thromb Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 223-9 Citation Subset: IM |
Affiliation:
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Department of Clinical Pathology, Hospital La Fe, Valencia, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Cell Count Blood Viscosity* Erythrocyte Aggregation* Erythrocyte Deformability* Erythrocyte Indices Female Fibrinogen / analysis* Hematocrit Humans Hypertension / blood* Male Middle Aged Vascular Resistance |
| Chemical | |
Reg. No./Substance:
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9001-32-5/Fibrinogen |
| Comments/Corrections | |
Erratum In:
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Thromb Res 1993 Dec 1;72(5):473 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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