Document Detail

Hemophagocytosis and acute monoblastic leukemia.
MedLine Citation:
PMID:  2641706     Owner:  NLM     Status:  MEDLINE    
A 16-month-old girl presented with hepatosplenomegaly and pancytopenia. Bone marrow aspiration showed a florid increase in macrophages with marked hemophagocytosis. She subsequently improved spontaneously with no therapeutic intervention, but 2 months later presented with frank acute monoblastic leukemia. This case illustrates the difficulties in classifying malignancies of the monocyte-macrophage lineage and how hemophagocytosis can be the presenting feature of a range of diseases.
L Russell; N J Shaw; O B Eden
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric hematology and oncology     Volume:  6     ISSN:  0888-0018     ISO Abbreviation:  Pediatr Hematol Oncol     Publication Date:  1989  
Date Detail:
Created Date:  1990-10-10     Completed Date:  1990-10-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8700164     Medline TA:  Pediatr Hematol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  367-71     Citation Subset:  IM    
Department of Haematology, Royal Hospital for Sick Children, Edinburgh, Scotland.
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MeSH Terms
Leukemia, Monocytic, Acute / immunology*
Macrophages / immunology
Monocytes / immunology
Phagocytosis / immunology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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