| Hemophagocytic syndrome in classic dengue Fever. | |
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MedLine Citation:
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PMID: 22224008 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A 24-year-old previously healthy girl presented with persistent fever, headache, and jaundice. Rapid-test anti-dengue virus IgM antibody was positive but anti-dengue IgG was nonreactive, which is suggestive of primary dengue infection. There was clinical deterioration during empiric antibiotic and symptomatic therapy. Bone marrow examination demonstrated the presence of hemophagocytosis. Diagnosis of dengue fever with virus-associated hemophagocytic syndrome was made according to the diagnostic criteria of the HLH 2004 protocol of the Histiocyte Society. The patient recovered with corticosteroid therapy. A review of literature revealed only a handful of case reports that showed the evidence that this syndrome is caused by dengue virus. Our patient is an interesting case of hemophagocytic syndrome associated with classic dengue fever and contributes an additional case to the existing literature on this topic. This case highlights the need for increased awareness even in infections not typically associated with hemophagocytic syndrome. |
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Authors:
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Sayantan Ray; Supratip Kundu; Manjari Saha; Prantar Chakrabarti |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of global infectious diseases Volume: 3 ISSN: 0974-8245 ISO Abbreviation: J Glob Infect Dis Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2012-01-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101521436 Medline TA: J Glob Infect Dis Country: India |
Other Details:
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Languages: eng Pagination: 399-401 Citation Subset: - |
Affiliation:
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Department of Medicine, Medical College and Hospital, West Bengal, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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