| Hemophagocytic syndrome: a cause of pancytopenia in human ehrlichiosis. | |
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MedLine Citation:
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PMID: 1951324 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 67-year-old white man with human ehrlichiosis infection complicated by pancytopenia, hemophagocytic syndrome, disseminated intravascular coagulopathy and septic shock is presented. The patient had been on a three-week camping trip to California, Colorado, Utah, and New Mexico. The diagnosis of human ehrlichiosis was confirmed by sixteen-fold rise in antibody titer to Ehrlichia canis, and supported by the characteristic cytoplasmic inclusions. Human ehrlichiosis should be considered in the differential diagnosis in patients with fever and cytopenia associated with hemophagocytosis. Pancytopenia associated with ehrlichiosis is transient; however, it may be severe, and appears to be associated with destruction of normal blood elements. |
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Authors:
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K C Abbott; S J Vukelja; C E Smith; C K McAllister; K A Konkol; T J O'Rourke; C J Holland; M Ristic |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of hematology Volume: 38 ISSN: 0361-8609 ISO Abbreviation: Am. J. Hematol. Publication Date: 1991 Nov |
Date Detail:
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Created Date: 1991-11-27 Completed Date: 1991-11-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7610369 Medline TA: Am J Hematol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 230-4 Citation Subset: IM |
Affiliation:
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Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antibodies, Bacterial / analysis Blood Cell Count Bone Marrow / pathology Ehrlichiosis / complications* Histiocytosis, Non-Langerhans-Cell / etiology*, microbiology, pathology Humans Male Pancytopenia / blood, etiology* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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