Document Detail

Hemophagocytic syndrome: a cause for fatal outcome in tuberculosis.
MedLine Citation:
PMID:  19332934     Owner:  NLM     Status:  MEDLINE    
Hemophagocytic syndrome is rare syndrome characterized by unregulated proliferation and activation of macrophages and phagocytosis of the platelet, erythrocytes, lymphocytes and their hematopoietic precursors in the bone marrow, resulting in cytopenias. It is associated with stimuli-like infections, malignancies and immunocompromised states. We present here a case of generalized lymphadenopathy, hepatosplenomegaly and progressive cytopenias in a 17-year-old male.
Anupama P Gupta; S N Parate; S K Bobhate;
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of pathology & microbiology     Volume:  52     ISSN:  0974-5130     ISO Abbreviation:  Indian J Pathol Microbiol     Publication Date:    2009 Apr-Jun
Date Detail:
Created Date:  2009-03-31     Completed Date:  2009-05-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7605904     Medline TA:  Indian J Pathol Microbiol     Country:  India    
Other Details:
Languages:  eng     Pagination:  260-2     Citation Subset:  IM    
Department of Pathology, Government Medical College, Nagpur, India.
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MeSH Terms
Fatal Outcome
Hepatomegaly / etiology
Lymphatic Diseases / etiology
Lymphohistiocytosis, Hemophagocytic / complications*,  diagnosis*,  pathology
Pancytopenia / etiology
Splenomegaly / etiology
Tuberculosis / complications*,  diagnosis*

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