| Hemophagocytic syndrome associated with cytomegalovirus infection in a severely immunocompromised AIDS patient: case report. | |
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MedLine Citation:
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PMID: 19578635 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hemophagocytic syndrome is a clinical condition characterized by the infiltration of the bone marrow and reticuloendothelial system by macrophages and activated histiocytes, leading to uncontrolled phagocytosis of platelets, erythrocytes, lymphocytes and precursor cells. It is a severe inflammatory and aggressive condition, characterized by high fever, hepatosplenomegaly, lymphadenopathy and cytopenia, and it may lead to organ dysfunction. This syndrome is classified as familial or acquired; the latter is more frequent and is associated with diverse conditions, such as infections, malignancies and rheumatic diseases. We report a case of HLH associated with cytomegalovirus infection in a patient with acquired-immunodeficiency syndrome and Burkitt's lymphoma. |
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Authors:
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Marcus V F Nogueira; Laira Vidal; Bruno Terra; Thiago Pagot; Jorge I F Salluh; Márcio Soares |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases Volume: 13 ISSN: 1678-4391 ISO Abbreviation: Braz J Infect Dis Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-07-06 Completed Date: 2009-08-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9812937 Medline TA: Braz J Infect Dis Country: Brazil |
Other Details:
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Languages: eng Pagination: 72-3 Citation Subset: IM |
Affiliation:
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National Institute of Cancer, Rio de Janeiro, RJ, Brazil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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AIDS-Related Opportunistic Infections
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complications,
diagnosis* Adult Burkitt Lymphoma / complications Cytomegalovirus Infections / complications, diagnosis* Humans Immunocompromised Host* Lymphohistiocytosis, Hemophagocytic / diagnosis*, etiology Male Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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