Document Detail

Hemophagocytic Lymphohistiocytosis (HLH) Associated with Plasmodium vivax Infection: Case Report and Review of the Literature.
MedLine Citation:
PMID:  22247919     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Hemophagocytic lymphohistiocytosis (HLH) is an unusual syndrome characterized by fever, hepatosplenomegaly, cytopenias, hypertriglyceridemia, hypofibrinogenemia, and pathologic findings of hemophagocytosis in the bone marrow and other tissues. HLH may be familial or associated with different types of infections, autoimmune disorders, or malignancies. Infection-associated HLH has been reported in various viral, bacterial, fungal, and parasitic infections, and case reports of parasitic infections implicated in HLH include rare cases from Plasmodium vivax infection, which occasionally affects both military personnel and civilians in Korea. We describe an unusual case of HLH resulting from Plasmodium vivax infection and review the literature. This case suggests that clinical suspicion of HLH is important when P. vivax infection is accompanied by cytopenias. Administration of antimalarial drugs may prevent irreversible end organ damage resulting from P. vivax-associated HLH.
Pil Soo Sung; In Ho Kim; Jae Ho Lee; Jong Won Park
Related Documents :
21857479 - Percutaneous endoscopic gastrostomy and peristomal infection: an avoidable complication...
21825059 - Enhanced neutrophil longevity and recruitment contribute to the severity of oviduct pat...
22244689 - Vaccinia viruses isolated from skin infection in horses produced cutaneous and systemic...
22208559 - The burden of moderate-to-heavy soil-transmitted helminth infections among rural malays...
21605179 - Characteristics of paecilomyces lilacinus infection comparing immunocompetent with immu...
22049899 - Enteric fever with severe pancytopenia in a four year girl.
23764419 - Infection and transmission dynamics of rkshv.219 in primary endothelial cells.
21349099 - Immunology of toxoplasma gondii.
6414319 - Effects of serum from treated patients on antibody-dependent cell adherence to the infe...
Publication Detail:
Type:  Journal Article     Date:  2011-12-26
Journal Detail:
Title:  Chonnam medical journal     Volume:  47     ISSN:  2233-7393     ISO Abbreviation:  Chonnam Med J     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-01-16     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101564659     Medline TA:  Chonnam Med J     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  173-6     Citation Subset:  -    
Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Incomplete distal renal tubular acidosis with nephrocalcinosis.
Next Document:  Cause of chest pain in a patient with previous myocardial infarction: look outside the heart for ext...