| Hemolytic uremic syndrome in a patient with systemic sclerosis treated with cyclosporin A. | |
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MedLine Citation:
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PMID: 1357898 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The case is presented of a 48-year-old female suffering from diffuse cutaneous systemic sclerosis (diffuse scleroderma) since 8 years, who went into renal failure as part of hemolytic uremic syndrome following 3 weeks' treatment with 3.8 mg/kg cyclosporin A. Hemolytic uremic syndrome has previously been described in transplant patients receiving cyclosporin A. There are also four cases reported in the literature of renal failure developing in middle aged females with diffuse cutaneous systemic sclerosis after short-term use of low dosage cyclosporin A treatment. It is suggested, that it may be wise not to use cyclosporin A to this category of patients, in which it can not be ruled out, that even a low dose therapy may trigger the rapid onset of scleroderma renal crisis or as in our case provoke hemolytic uremic syndrome. |
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Authors:
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H Zachariae; H E Hansen; T S Olsen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 72 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-11-23 Completed Date: 1992-11-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 307-9 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Marselisborg hospital, Aarhus, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Cyclosporine / adverse effects* Female Fibrosis Hemolytic-Uremic Syndrome / chemically induced* Humans Kidney / pathology Middle Aged Scleroderma, Systemic / drug therapy*, pathology |
| Chemical | |
Reg. No./Substance:
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59865-13-3/Cyclosporine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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