Document Detail

Hemolytic anemia produced by regurgitation through transposed chordae tendineae.
MedLine Citation:
PMID:  16359054     Owner:  NLM     Status:  MEDLINE    
Hemolytic anemia after mitral repair and annuloplasty ring placement is very uncommon, and rarely described. The case is presented of a 53-year-old woman who developed severe mitral regurgitation and transfusion-dependent hemolytic anemia following mitral valve repair with a Carpentier-Edwards annuloplasty ring, which included transposition of chordae tendineae from the posterior leaflet to the anterior leaflet. Transesophageal echocardiography suggested that the transposed chordae tethered the anterior leaflet, causing malcoaptation of the leaflets. This resulted in central regurgitation divided by the chordae tendineae, producing two turbulent flow jets causing hemolysis. At reoperation, these chordae were removed and two longer Gortex neochordae to the anterior leaflet were placed with subsequent resolution of the anemia. To the authors' knowledge, this is the first case of hemolytic anemia caused by transposed mitral valve chordae tendineae from the posterior to the anterior leaflet.
James P Birkbeck; Michael E Gorton; James L Vacek
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  14     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-12-19     Completed Date:  2006-02-21     Revised Date:  2006-05-04    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  749-51     Citation Subset:  IM    
Division of Cardiology, Department of Internal Medicine, University of Kansas Hospital, Kansas City, Kansas 66160, USA.
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MeSH Terms
Anemia, Hemolytic / etiology*,  therapy
Blood Transfusion
Chordae Tendineae / surgery*
Echocardiography, Transesophageal
Heart Valve Prosthesis Implantation / adverse effects*
Middle Aged
Mitral Valve / surgery*
Mitral Valve Insufficiency / surgery*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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