Document Detail

Hemolysis of rabbit erythrocytes induced by cigarette smoke.
MedLine Citation:
PMID:  2266788     Owner:  NLM     Status:  MEDLINE    
Cigarette smoke has been found to induce the hemolysis of rabbit erythrocytes. The particulate phase had more profound effect than the gas phase. Neither free radical scavengers such as ascorbic acid, uric acid and water-soluble vitamin E analogue nor antioxidant enzymes such as catalase and superoxide dismutase suppressed the cigarette smoke-induced hemolysis, suggesting that free radicals, hydrogen peroxide, and superoxide were not the active species.
S Minamisawa; E Komuro; E Niki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Life sciences     Volume:  47     ISSN:  0024-3205     ISO Abbreviation:  Life Sci.     Publication Date:  1990  
Date Detail:
Created Date:  1991-02-14     Completed Date:  1991-02-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375521     Medline TA:  Life Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2207-15     Citation Subset:  IM    
Department of Reaction Chemistry, Faculty of Engineering, University of Tokyo, Japan.
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MeSH Terms
Ascorbic Acid / pharmacology
Aspartate Aminotransferases / metabolism
Catalase / pharmacology
Erythrocytes* / drug effects
Free Radicals
Hemoglobins / metabolism
Plants, Toxic*
Potassium / metabolism
Smoke / adverse effects*
Superoxide Dismutase / pharmacology
Uric Acid / pharmacology
Vitamin E / pharmacology
Reg. No./Substance:
0/Free Radicals; 0/Hemoglobins; 0/Smoke; 1406-18-4/Vitamin E; 50-81-7/Ascorbic Acid; 69-93-2/Uric Acid; 7440-09-7/Potassium; EC; EC Dismutase; EC Aminotransferases

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