| Hemolysis and elevated transaminases imitating severe preeclampsia. | |
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MedLine Citation:
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PMID: 19155951 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Illnesses coincident with pregnancy may present similarly to preeclampsia or may be mistaken for severe preeclampsia or hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. Distinguishing these imitators from preeclampsia is important to allow for appropriate treatment and to avoid unnecessary delivery. CASE: A primigravida at 32 2/7 weeks of gestation transferred to our institution with flu-like symptoms, anemia, jaundice, and elevated liver function tests. The team caring for her was concerned about HELLP or acute fatty liver. After extensive workup, she was found to have a cold agglutinin. Her laboratory test results improved, and she was discharged undelivered with a presumptive diagnosis of cold agglutinin autoimmune hemolytic anemia. CONCLUSION: When patients present with atypical features of HELLP syndrome, clinicians should take time to consider other "imitators of preeclampsia" before rapidly progressing to delivery to avoid inappropriate treatment of the disorder. |
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Authors:
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Bridget Kamen; Mark A Karwal; Jerome Yankowitz |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 113 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-01-21 Completed Date: 2009-02-23 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 545-7 Citation Subset: AIM; IM |
Affiliation:
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Departments of Internal Medicine, University of Iowa College of Medicine Iowa City, Iowa, USA. bridget-kamen@uiowa.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alanine Transaminase / blood Anemia, Hemolytic, Autoimmune / diagnosis*, enzymology Aspartate Aminotransferases / blood Diagnosis, Differential Female HELLP Syndrome / diagnosis* Humans Liver Function Tests Pregnancy |
| Chemical | |
Reg. No./Substance:
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EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.2/Alanine Transaminase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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