| Hemolysate-induced release of prostaglandinlike substances from the canine cerebral arteries. | |
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MedLine Citation:
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PMID: 3975836 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The release of prostaglandinlike substances from canine pial arteries that was induced by exposure of the pial arteries to red blood cell hemolysate was estimated by using a superfusion technique for prostaglandin bioassay. The assay organs used were strips of rat stomach for prostaglandin E2- or prostaglandin F2 alpha-like substances, strips of dog coronary artery for prostaglandin I2-like substance, and strips of dog ileum for prostaglandin F2 alpha-like substance. The substances released from the canine pial arteries induced contractions in rat stomach strips and relaxations in canine coronary arterial strips, whereas they did not induce any response in canine ileal strips. The equivalent prostaglandin E2 doses for the contractions of the rat stomach strips and the equivalent prostaglandin I2 doses for the relaxations of the canine coronary arterial strips were 125.2 +/- 19.4 (n = 8) and 59.5 +/- 16.4 (n = 6) pmol/g wet wt +/- SEM, respectively. |
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Authors:
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S Okamoto; H Handa; Y Handa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Surgical neurology Volume: 23 ISSN: 0090-3019 ISO Abbreviation: Surg Neurol Publication Date: 1985 Apr |
Date Detail:
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Created Date: 1985-04-25 Completed Date: 1985-04-25 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0367070 Medline TA: Surg Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 421-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cerebral Arteries / metabolism* Coronary Vessels / drug effects, physiology Dogs Erythrocytes / physiology* Female Ileum / drug effects, physiology Male Prostaglandins / metabolism*, pharmacology Stomach / drug effects, physiology |
| Chemical | |
Reg. No./Substance:
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0/Prostaglandins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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