| Hemoglobin köln and pregnancy. | |
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MedLine Citation:
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PMID: 19038075 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Patients with hemoglobin Köln usually present with a mild hemolytic anemia characterized by reticulocytosis, splenomegaly, and elevated circulating bilirubin and lactate dehydrogenase levels. There have been no previous reports of whether these characteristics change during pregnancy and whether pregnancy provides any specific concerns for patients with hemoglobin Köln. CASE: A 36-year-old woman of Chinese origin with a twin pregnancy had an uneventful antenatal course except for the presence of thrombocytopenia that was not completely investigated. During elective repeat Caesarean section, it was noted that the woman had a low SpO2 on pulse oximetry despite a normal arterial oxygen tension from arterial blood gas measurement. Subsequent investigations identified the woman as a heterozygous carrier for hemoglobin Köln. CONCLUSION: Women with hemoglobin Köln who become pregnant require close monitoring of the maternal platelet count and an awareness of the falsely low SpO2 on pulse oximetry to ensure a favourable outcome. |
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Authors:
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Vincent Y T Cheung; Jeffrey A Silverman |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC Volume: 30 ISSN: 1701-2163 ISO Abbreviation: J Obstet Gynaecol Can Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-11-28 Completed Date: 2009-02-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101126664 Medline TA: J Obstet Gynaecol Can Country: Canada |
Other Details:
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Languages: eng Pagination: 907-9 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, North York General Hospital, University of Toronto, Toronto ON. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carrier State* Female Hemoglobins, Abnormal / genetics* Heterozygote Humans Oximetry Oxygen / blood Pregnancy Pregnancy Complications, Hematologic / genetics* Pregnancy, Multiple Thrombocytopenia / genetics* Twins |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins, Abnormal; 7782-44-7/Oxygen; 9035-00-1/hemoglobin Koln |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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