| Hemoglobin E disorders in Eastern Uttar Pradesh. | |
| | |
MedLine Citation:
|
PMID: 19136801 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The distribution of hemoglobin E (alpha2beta2 26Glu (R)Lys ) is mostly restricted to Northeastern India. While evaluating the patients of jaundice, we came across two cases of hemoglobin E (Hb E) disorders. The first case is in a 22-year-old Bengali male and the second case of Hb E/beta thalassemia in a 5-year-old Hindu boy. The family study revealed Hb E trait in both the parents of Case 1, whereas in Case 2, the father was found to have Hb E trait and the mother had beta -thalassemia minor, thus confirming the diagnosis. Herein, we present the laboratory diagnosis and comparative data of the spectrum of Hb E disorders (i.e., heterozygous Hb E trait, homozygous Hb E disease and compound heterozygous Hb E/beta -thalassemia) that was found in our index cases and their parents. |
| | |
Authors:
|
Shashikant C U Patne; Jyoti Shukla |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Indian journal of pathology & microbiology Volume: 52 ISSN: 0974-5130 ISO Abbreviation: Indian J Pathol Microbiol Publication Date: 2009 Jan-Mar |
Date Detail:
|
Created Date: 2009-01-12 Completed Date: 2009-03-12 Revised Date: 2009-05-21 |
Medline Journal Info:
|
Nlm Unique ID: 7605904 Medline TA: Indian J Pathol Microbiol Country: India |
Other Details:
|
Languages: eng Pagination: 110-2 Citation Subset: IM |
Affiliation:
|
Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi - 221005, Uttar Pradesh, India. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Amino Acid Substitution / genetics Family Health Hemoglobin E / genetics* Hemoglobinopathies / diagnosis* Humans India Male Mutation, Missense Parents Young Adult |
| Chemical | |
Reg. No./Substance:
|
9034-61-1/Hemoglobin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Central neurocytoma in the vermis of the cerebellum.
Next Document: Transient thrombocytosis with megathrombocytes in a case of acute myeloblastic leukemia.