Document Detail


Hemoglobin Bart's in a Brazilian black population.
MedLine Citation:
PMID:  2095287     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hemoglobin Bart's was measured spectrophotometrically after electrophoresis on cellulose acetate strips in cord blood from 320 full-term randomly selected black newborns from the University Hospital of Campinas, State of São Paulo, in the southeast of Brazil. Hb Bart's was detected in 38 of the 320 newborns (11.9%), with the levels presenting the following bimodal distribution: 10.3% of the infants in the 1-3.5% range and 1.6% in the 5-10% range. The data suggest that the frequency of alpha-thalassemia gene in the Brazilian black population is 0.125 since individuals with Bart's Hb in the 5-10% range are usually alpha(+)-thalassemia homozygotes.
Authors:
M F Sonati; F F Costa
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]     Volume:  23     ISSN:  0100-879X     ISO Abbreviation:  Braz. J. Med. Biol. Res.     Publication Date:  1990  
Date Detail:
Created Date:  1991-07-05     Completed Date:  1991-07-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8112917     Medline TA:  Braz J Med Biol Res     Country:  BRAZIL    
Other Details:
Languages:  eng     Pagination:  395-6     Citation Subset:  IM    
Affiliation:
Departamento de Patologia Clínica, Faculdade de Medicina, Universidade Estadual de Campinas, Brasil.
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MeSH Terms
Descriptor/Qualifier:
African Continental Ancestry Group*
Brazil / epidemiology
Hemoglobins, Abnormal / analysis*
Humans
Infant, Newborn
Prevalence
Thalassemia / epidemiology
Chemical
Reg. No./Substance:
0/Hemoglobins, Abnormal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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