| Hemoglobin Bart's in a Brazilian black population. | |
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MedLine Citation:
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PMID: 2095287 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hemoglobin Bart's was measured spectrophotometrically after electrophoresis on cellulose acetate strips in cord blood from 320 full-term randomly selected black newborns from the University Hospital of Campinas, State of São Paulo, in the southeast of Brazil. Hb Bart's was detected in 38 of the 320 newborns (11.9%), with the levels presenting the following bimodal distribution: 10.3% of the infants in the 1-3.5% range and 1.6% in the 5-10% range. The data suggest that the frequency of alpha-thalassemia gene in the Brazilian black population is 0.125 since individuals with Bart's Hb in the 5-10% range are usually alpha(+)-thalassemia homozygotes. |
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Authors:
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M F Sonati; F F Costa |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] Volume: 23 ISSN: 0100-879X ISO Abbreviation: Braz. J. Med. Biol. Res. Publication Date: 1990 |
Date Detail:
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Created Date: 1991-07-05 Completed Date: 1991-07-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8112917 Medline TA: Braz J Med Biol Res Country: BRAZIL |
Other Details:
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Languages: eng Pagination: 395-6 Citation Subset: IM |
Affiliation:
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Departamento de Patologia Clínica, Faculdade de Medicina, Universidade Estadual de Campinas, Brasil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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African Continental Ancestry Group* Brazil / epidemiology Hemoglobins, Abnormal / analysis* Humans Infant, Newborn Prevalence Thalassemia / epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins, Abnormal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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