Document Detail

Hemodynamics and jugular venous oxygen saturation during carotid endarterectomy: a comparison between general and locoregional anesthesia.
MedLine Citation:
PMID:  20502409     Owner:  NLM     Status:  MEDLINE    
AIM: To study hemodynamic and blood oxygenation changes in patients undergoing carotid endarterectomy (CEA) under general (GA) or locoregional (LRA) anesthesia. METHODS: Prospective non-randomized study including 50 patients undergoing CEA (31 men, mean age 72 (range 50-84) years-old under GA (N.=23) or LRA (N.=27). Systemic blood pressure, ECG, venous oxygen saturation in the ipsilateral jugular bulb and pulse-oximetry were monitored. Blood-gas analysis was done from blood obtained from the radial artery and ipsilateral jugular vein. RESULTS: Pulse rate and systemic systolic blood pressure were higher in LRA compared to the GA before, during and after cross clamping (P<0.05). Seven GA patients required dopamine-infusion to maintain systolic blood pressure >120 mmHg. Jugular venous saturation was initially identical in both groups, but decreased significantly upon cross clamping in LRA compared to GA (P<0.05). This difference remained at least 3 minutes after cross clamp release (P<0.05). CONCLUSION: Patients under LRA seem to have increased sympathetic activity compared to patients under GA, as expressed by higher pulse rates and systolic blood pressures. Jugular venous saturation was lower during clamping of LRA patients. The differences were small and concur with the near-equality findings in studies analysing the clinical outcome.
N V Dias; T Kölbel; I Gonçalves; M Chew; J Wistrand; P S Brunkwall
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  29     ISSN:  1827-1839     ISO Abbreviation:  Int Angiol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-26     Completed Date:  2010-09-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  232-8     Citation Subset:  IM    
Vascular Center Malmö-Lund, Malmö University Hospital, Malmö, Sweden.
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MeSH Terms
Aged, 80 and over
Anesthesia, Conduction*
Anesthesia, General*
Blood Pressure
Cardiotonic Agents / administration & dosage
Carotid Stenosis / blood,  physiopathology,  surgery*
Dopamine / administration & dosage
Endarterectomy, Carotid*
Heart Rate
Jugular Veins
Middle Aged
Oxygen / blood*
Prospective Studies
Severity of Illness Index
Sympathetic Nervous System / physiopathology
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Cardiotonic Agents; 7782-44-7/Oxygen

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