Document Detail

Hemodynamic variations due to spiral blood flow through four patient-specific bifurcated stent graft configurations for the treatment of abdominal aortic aneurysms.
MedLine Citation:
PMID:  23255342     Owner:  NLM     Status:  MEDLINE    
Endovascular repair is now a recognised procedure for treating abdominal aortic aneurysms. However, post-operative complications such as stent graft migration and thrombus may still occur. To assess these complications numerically, the correct input boundary conditions, which include the full human aorta with associated branching, should be included. Four patient-specific computed tomography scanned bifurcated stent grafts (SGs) were modelled and attached onto a full human aorta, which included the ascending, aortic arch and descending aortas. Two of the SG geometries had a twisted leg configuration, while the other two had conventional nontwisted leg configurations. Computational fluid dynamics was completed for both geometries and the hemodynamics assessed. The complexity of the flow patterns and secondary flows were influenced by the inclusion of the full human aorta at the SG proximal section. During the decelerating phase significant recirculations occurred along the main body of all SG configurations. The inclusion of the full human aorta did not impact the velocity contours within the distal legs and there was no difference in drag forces with the SG containing the full human aorta and those without. A twisted leg configuration further promoted a spiral flow formation along its distal legs.
Florian Stefanov; Tim McGloughlin; Patrick Delassus; Liam Morris
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-12-18
Journal Detail:
Title:  International journal for numerical methods in biomedical engineering     Volume:  29     ISSN:  2040-7947     ISO Abbreviation:  Int J Numer Method Biomed Eng     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-02-06     Completed Date:  2013-09-03     Revised Date:  2014-07-09    
Medline Journal Info:
Nlm Unique ID:  101530293     Medline TA:  Int J Numer Method Biomed Eng     Country:  England    
Other Details:
Languages:  eng     Pagination:  179-96     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 John Wiley & Sons, Ltd.
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MeSH Terms
Aorta, Thoracic / physiopathology,  radiography
Aortic Aneurysm, Abdominal / radiography,  therapy*
Blood Flow Velocity
Blood Vessel Prosthesis
Computer Simulation
Radiographic Image Enhancement
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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