Document Detail

Hemodynamic strategies in blood pressure regulation during orthostatic challenge in women.
MedLine Citation:
PMID:  9263619     Owner:  NLM     Status:  MEDLINE    
Several studies indicate that carotid baroreflex responsiveness is a good predictor of orthostatic tolerance. Two groups of healthy women with high (HI) and low (LO) carotid baroreflex responsiveness were studied (a) to determine any differences in the level of orthostatic tolerance of the two groups, and (b) to study the hemodynamic strategies used by HI and LO responders to regulate arterial pressure during the orthostatic challenge of lower body negative pressure (LBNP). Orthostatic tolerance was similar between the two groups, whereas the hemodynamic strategies recruited to maintain blood pressure at -40 mmHg LBNP differed: HI responders exhibited greater LBNP-induced decreases in stroke volume and cardiac output, as well as a greater increase in peripheral resistance compared to LO responders (p < .05). In addition, a significant increase in plasma renin activity during LBNP was found in the HI responders only. No significant between-group differences were found in arterial and cardiopulmonary control of vascular resistance or arterial baroreflex control of heart rate during LBNP.
T L Culham; G K Savard
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian journal of applied physiology = Revue canadienne de physiologie appliquée     Volume:  22     ISSN:  1066-7814     ISO Abbreviation:  Can J Appl Physiol     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-10-06     Completed Date:  1997-10-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9306274     Medline TA:  Can J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  351-67     Citation Subset:  IM; S    
School of Physical and Health Education, Queen's University, Kingston, ON.
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MeSH Terms
Blood Pressure / physiology*
Cardiac Output / physiology
Carotid Arteries / physiology*
Heart Rate / physiology
Hypotension, Orthostatic / physiopathology
Lower Body Negative Pressure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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