Document Detail

Hemodynamic status susceptible to slowing of heart rate during thermodilution cardiac output determination in anesthetized patients.
MedLine Citation:
PMID:  2379397     Owner:  NLM     Status:  MEDLINE    
To identify hemodynamic variables that might indicate susceptibility to slowing of heart rate (HR) and to mean arterial pressure (MAP) decrease caused by cold injectate during thermodilution (TD) cardiac output determination, we measured hemodynamic variables in 32 anesthetized patients undergoing major surgery. A total of 608 cardiac output determinations were evaluated for any relationship between the magnitude of HR decreases and basal hemodynamic variables. The magnitude of HR decrease was pronounced in low cardiac index (CI), low mean pulmonary artery pressure (MPAP), and high systemic vascular resistance index (SVRI). Although there was some decrease in MAP associated with cold injectate, neither changes in SVRI nor those in the other hemodynamic variables correlated with the decreases in MAP. These results suggest that decreased CI and MPAP associated with elevated SVRI may be more susceptible to slowing of HR during cardiac output determination by TD in anesthetized patients.
T Nishikawa; S Dohi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  18     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-09-12     Completed Date:  1990-09-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  841-4     Citation Subset:  AIM; IM    
Department of Anesthesiology, University of Tsukuba, Ibaraki, Japan.
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MeSH Terms
Anesthesia, General*
Blood Pressure
Cardiac Output*
Cold Temperature
Glucose / administration & dosage,  diagnostic use
Heart Rate*
Middle Aged
Thermodilution* / methods
Vascular Resistance
Reg. No./Substance:

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