Document Detail

Hemodynamic response to treadmill exercise in normal volunteers: an assessment by Doppler ultrasonic measurement of ascending aortic blood velocity and acceleration.
MedLine Citation:
PMID:  3055908     Owner:  NLM     Status:  MEDLINE    
Accurate assessment of ascending aortic blood velocity indices and reproducibility of a Doppler ultrasonic system during exercise were determined; the Doppler technique was then used to assess the effects of age, sex, and beta blockade on exercise hemodynamics. Doppler-determined velocity correlated well with an invasive electromagnetic system. Reproducibility of Doppler variables during three exercise tests was high (coefficient of variation less than 10%) and did not deteriorate appreciably with exercise. Peak velocity (PV) and maximum acceleration (MA) were inversely related to age, the relationship being more significant during exercise, whereas the systolic velocity integral showed no such relationship either at rest or during exercise. Doppler variables showed no difference between sexes, except at high levels of exercise. Beta blockade markedly attenuated the exercise response as shown by significant decreases in both MA and PV during exercise. The Doppler velocity data presented in this study provide a reference against which previously documented changes in exercising ischemic patients can be better related.
N Mehta; G Boyle; D Bennett; S Gilmour; M I Noble; C M Mills; S Pugh
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  116     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1988 Nov 
Date Detail:
Created Date:  1988-12-05     Completed Date:  1988-12-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1298-307     Citation Subset:  AIM; IM    
Department of Medicine 1, St. George's Hospital Medical School, Midhurst, Sussex, England.
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MeSH Terms
Age Factors
Aorta / physiology*
Atenolol / diagnostic use
Blood Flow Velocity
Exercise Test
Middle Aged
Sex Factors
Stroke Volume*
Reg. No./Substance:

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