Document Detail

Hemodynamic response to exercise as measured by the solar IKG impedance cardiography module and correlation with metabolic variables.
MedLine Citation:
PMID:  17086447     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Impedance Cardiography (ICG) has been shown to be a feasible and accurate method for non-invasive measurement of cardiac index (CI). Aim of this investigation was the correlation of hemodynamic variables under exercise as measured by a specific ICG-monitor (Solar IKG-Modul, Version 3.0, GE-Healthcare, Freiburg, Germany) with metabolic variables. METHODS: Ten healthy volunteers were included in the investigation doing ergometer exercise (5 min equilibration followed by 5 min each at 50, 75, 100 and 125 W). Hemodynamic parameters were obtained by ICG. Metabolic variables were assessed by indirect calorimetry with the Deltatrac II Metabolic monitor using a helmet system for spontaneous respiration. RESULTS: CI increased throughout exercise (baseline: 3.0 +/- 0.4 l/min/m(2); 125 W: 4.8 +/- 0.5 l/min/m(2)). Heart rate (baseline: 87.2 +/- 13.4 bpm; 125 W: 152.7 +/- 22.4 bpm) and contractility (velocity index) (baseline: 48.9 +/- 9.3/1000 s; 125 W: 70.5 +/- 10.0/1000 s) showed a continuous rise while the stroke index decreased after an initial rise (baseline: 35.0 +/- 4.6 ml/m(2); 50 W: 37.6 +/- 4.9 ml/m(2); 75 W: 41.2 +/- 5.9 ml/m(2); 125 W: 32.3 +/- 6.1 ml/m(2)). VO(2) (baseline: 335.2 +/- 84.1 ml/min; 125 W: 1298.9 +/- 282.3 ml/min) and VCO(2)(baseline: 255.4 +/- 74.5 ml/min; 125 W: 1342.5 +/- 282.5 ml/min) increased throughout exercise. There was a good correlation in the individual fits between hemodynamic and metabolic variables. CONCLUSION: CI in healthy volunteers, as measured by the Solar IKG-Modul, correlates well with O(2)-consumption and CO(2)-production in individual subjects, thus indicating the metabolic needs under exercise conditions in healthy individuals.
Stephan Ziegeler; Ulrich Grundmann; Oliver Fuerst; Alexander Raddatz; Sascha Kreuer
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Publication Detail:
Type:  Journal Article     Date:  2006-11-04
Journal Detail:
Title:  Journal of clinical monitoring and computing     Volume:  21     ISSN:  1387-1307     ISO Abbreviation:  J Clin Monit Comput     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-31     Completed Date:  2007-10-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9806357     Medline TA:  J Clin Monit Comput     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  13-20     Citation Subset:  IM    
Department of Anesthesiology and Intensive Care Medicine, University of Saarland, 66421, Homburg/Saar, Germany.
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MeSH Terms
Carbon Dioxide / chemistry
Cardiac Output
Cardiography, Impedance*
Heart Rate
Monitoring, Ambulatory / methods*
Oxygen / chemistry
Oxygen Consumption
Regression Analysis
Stroke Volume
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

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