Document Detail

Hemodynamic and pulmonary changes during and after laparoscopic cholecystectomy. A comparison with traditional surgery.
MedLine Citation:
PMID:  9479724     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The cardiopulmonary changes experienced by patients who undergo laparoscopic cholecystectomy (LC) and the prognostic value of patient characteristics are not well understood. METHODS: Cardiorespiratory changes were investigated in 120 patients undergoing LC or open cholecystectomy (OC). The results and their relation to patient variables were statistically evaluated. RESULTS: The most significant cardiorespiratory changes were (A-a)PO2 increase during OC; decrease of pH and compliance and increase of peak airway pressure during LC; impairment of arterial blood gas mean values and respiratory muscle strength; atelectasis and pneumonia (five cases) after OC; and lamellar atelectasis (two cases) after LC. Significant adverse prognostic factors related to intra- and postoperative LC cardiorespiratory changes were ASA class greater than I, FEF75-85% < 900 ml, and PaO2 < 10.4 kPa (PPV, 71.4% and 46.6%, respectively). CONCLUSIONS: LC carries no significant cardiorespiratory changes provided that intraoperative monitoring of hemodynamics and respiratory parameters is done for the study of blood gas values in all patients at risk.
P Volpino; V Cangemi; N D'Andrea; B Cangemi; G Piat
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Surgical endoscopy     Volume:  12     ISSN:  0930-2794     ISO Abbreviation:  Surg Endosc     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-04-15     Completed Date:  1998-04-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8806653     Medline TA:  Surg Endosc     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  119-23     Citation Subset:  IM    
First Department of Surgery, University of Rome La Sapienza, Italy.
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MeSH Terms
Carbon Dioxide / administration & dosage
Cholecystectomy, Laparoscopic*
Follow-Up Studies
Hemodynamics / physiology*
Intraoperative Complications / physiopathology
Lung / physiopathology*
Middle Aged
Pneumoperitoneum, Artificial
Postoperative Complications / physiopathology
Respiratory Function Tests
Retrospective Studies
Risk Factors
Reg. No./Substance:
124-38-9/Carbon Dioxide
Comment In:
Surg Endosc. 1998 Feb;12(2):93-4   [PMID:  9479718 ]

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